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Could a new 'imaginary meal' pill solve the obesity crisis? We chat to Multi-Media Health Specialist, Dr. Darren Green about the new pill & the best weight-loss techniques out there. http://www.expressoshow.com

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Pfizer on Friday said it would stop developing the twice-daily version of its experimental weight loss pill after obese patients taking the drug lost weight but had trouble tolerating the drug in a mid-stage clinical study. The drugmaker observed high rates of adverse side effects, which were mostly mild and gastrointestinal, among patients. A significant share of patients also stopped taking the drug in the trial."At this time, twice-daily danuglipron formulation will not advance into Phase 3 studies," the company said. But Pfizer said it still plans to release phase two trial data on a once-a-day version of the drug in the first half of 2024, which will "inform a path forward." The pharmaceutical giant will wait to see that data before deciding whether to start a phase three study on the once-daily pill, which Wall Street views as the more competitive form of the treatment. Still, the data on the twice-daily drug is a blow to Pfizer's hopes to win a $10 billion slice of the booming weight loss drug market, which CEO Albert Bourla has said could grow to $90 billion. The company is betting on a successful weight loss pill to help it rebound from plummeting demand for its Covid products and a roughly 40% share price drop this year. But investors have been pessimistic about Pfizer's potential in the weight loss drug space since the company scrapped a different once-daily pill in June and proceeded with the less attractive danuglipron. Now, Friday's data puts Pfizer even further behind the dominant players in the weight loss drug market, Eli Lilly and Novo Nordisk, which are racing to develop more convenient pill versions of their blockbuster weight loss and diabetes injections. Pfizer's phase two trial on its twice-daily pill followed around 600 obese adults who did not have Type 2 diabetes. The trial examined the drug's effect on weight loss after 26 or 32 weeks, at different dosage amounts ranging from 40 milligrams to 200 milligrams. Like Novo Nordisk's Wegovy and Ozempic, Pfizer's pill works by mimicking a hormone produced in the gut called GLP-1, which signals to the brain when a person is full. All dose sizes of Pfizer's pill showed "statistically significant reductions" in body weight ranging from 6.9% to 11.7% at 32 weeks, and from 4.8% to 9.4% at 26 weeks. Meanwhile, patients on a placebo lost 8% to 13% of their body weight at 32 weeks and 5% to 9.5% at 26 weeks, Pfizer said. The company said high rates of adverse events were observed among patients in the study, with up to 73% experiencing nausea, up to 47% vomiting and up to 25% experiencing diarrhea. More than 50% of patients across all dose sizes stopped taking the pill, compared to roughly 40% among those on the placebo, according to Pfizer. No new safety issues were observed, and danuglipron was not associated with increased liver enzymes like Pfizer's other discontinued weight loss pill. All data is taken from the source: http://cnbc.com Article Link: https://www.cnbc.com/2023/12/01/pfizer-to-discontinue-twice-daily-version-of-weight-loss-pill.html #weight #newshour #newstodayheadlines #newstodayfox #newstodayupdate #newstodayworld #

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Let us get it clearly – if you are already on a ketogenic diet and want to improve your way to ketosis and stay that way in order to shed more pounds, take a look at Ketogenmax ACV: a combination of two mighty forces: the energy generated by ketosis and the potency of apple cider vinegar. In this article, we are going to read more about how you get to ketosis and maintain it by using Ketogenmax ACV.

The Benefits of Ketogenmax ACV

Ketogenmax ACV is specifically designed to boost ketosis. Ketosis is the metabolic state in which your body uses fat as fuel rather than carbohydrates. Ketogenmax ACV combines apple cider vinegar with a few key ingredients meant to assist in reaching and maintaining this state. Ketosis allows you to use fat as fuel instead of carbohydrates, thus getting you into optimal health.

Apple cider vinegar has long been used for its health benefits, including increased digestion, helping with weight loss and containing a small amount of sugar which helps to slightly regulate blood sugar levels too. If you want to add apple cider vinegar to your everyday routine then it can really help to increase ketone levels and can help with weight loss, when combined with a ketogenic diet.

It doesn’t only shave time off reaching your state of ketosis, but using Ketogenmax ACV also improves your natural detoxification mechanisms. You’ve probably heard about the great detoxifying properties that apple cider vinegar offers for your body: experience it for yourself.

How to Incorporate Ketogenmax ACV into Your Routine 12 Quick Weight Loss Tips Quick Ways To Lose Weight

You can integrate Ketogenmax ACV into your daily life by consuming two Ketogenmax ACV capsules with a glass of water before meals. This will maintain your current fat-burning processes and keep you in the state of ketosis all day long.

In addition to the Ketogenmax ACV capsules, you can incorporate apple cider vinegar in ACV foods such as mixing one tablespoon of ACV with water and honey to drink them, or use it as a salad dressing or a marinade.

But you should take it along with a healthy keto diet and exercise, thereby resulting in betterment of your results. By doing so you can get to your desired fitness and health targets in a faster and more effective manner.

FAQs About Ketogenmax ACV

Q: Is Ketogenmax ACV safe to use?

A: Yes, Ketogenmax ACV is made with all-natural ingredients. However, it is important to note that everyone’s reactions to supplements may differ, so you should consult your doctor to see if Ketogenmax ACV is compatible with your medication and health.

Q: How quickly will I see results with Ketogenmax ACV?

Q:What are the results of Keto Genmax ACV?A: When you use Keto Genmax ACV, it could take some people only a month to start seeing results in regards to their energy levels and weight. To ensure that you’ll get the results that you want to get, eat healthy and do regular exercise while taking the supplement.

Q: Can I take Ketogenmax ACV if I’m not following a ketogenic diet?

Q: Do you need to follow a ketogenic diet to benefit from Ketogenmax ACV or will it still have all of its weight loss- and detoxifying benefits if you eat normally? A: While Ketogenmax ACV was specifically designed to further assist in ketosis, it is of certain that you can still gain many of the benefits of being in ketosis and weight loss and colon cleansing regardless of what type of diet you follow. For best results though, you should use Ketogenmax ACV alongside a low-carb, high-fat diet.

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Check out this video on bad facial aging habits next! http://bit.ly/4iDk3Qw GLP-1 medications like Ozempic have grown massively in the weight loss industry. The question that many people ask, though, is whether GLP-1 medications will accelerate the effects of aging in the face as they lose weight. In today's video, Dr. Karam is sharing how GLP-1 medication works, what it could potentially do to the appearance of your face, and what to do to prevent or treat any unwanted facial aging side effects. 📅 For Dr. Karam’s virtual consultations and surgical pricing, please follow this link: https://www.drkaram.com/getting-started/ 🌟 Educate yourself on all things skincare by checking out the KaramMD Journal: https://karammdskin.com/blogs/expert-advice/ozempic-face-explained-how-to-reverse-facial-aging-after-weight-loss 🤩Achieve Younger, Healthier Skin with KaramMD Trifecta. Shop Here: https://karammdskin.com/ ✅ Learn More About Dr. Karam: https://www.drkaram.com/ 00:00 GLP-1 Medications 04:20How Facial Fat Loss Works 08:12 How Muscle Loss Works 09:56 Preventing Unwanted Effects of Facial Weight Loss 13:37 Treating Unwanted Effects of Facial Weight Loss 18:34 Patient Testimonial: Sandy 20:04 Key Takeaways

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