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The combined use of sodium-glucose transport protein 2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists may offer notable benefits for optimizing cardiovascular and renal outcomes in patients with diabetes, according to recent research. A collaborative meta-analysis of 12 trials from the SGLT2 Inhibitor Meta-Analysis Cardio-Renal Trialists’ Consortium (SMART-C) revealed consistent positive impacts on major adverse cardiovascular events, hospitalization for heart failure or cardiovascular death, chronic kidney disease progression, and the occurrence of adverse events with the combined use of SGLT2 inhibitors and GLP-1 receptor agonists. “That information probably provides the strongest and clearest evidence yet that these drugs have independent and additive effects, and should be used in combination to further optimize cardiorenal prognosis,” Brendon Neuen, MBBS, PhD, said to HCPLive. #Diabetes #ChronicKidneyDisease #HeartFailure #Cardiology #Nephrology https://www.hcplive.com/view/brendon-neuen-mbbs-phd-optimizing-cardiorenal-prognosis--glp-1-sglt2-combination https://www.hcplive.com/view/sglt2-inhibitor-glp-1-ra-combination-improves-cardiovascular-kidney-outcomes-diabetes

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Speaker: Aleksandros Mihilli, MD PGY-3 IM Resident No disclosures Objectives: •Understand how GLP-1RA function, and their use in diabetes and weight loss •Compare the available GLP-1RA in terms of efficacy, and when to use which •Look at future advancements in the field and what research is currently ongoing Click here to access CME evaluation and certificate: https://www.surveymonkey.com/r/VKTRN2P Accreditation Statement: The Northeast Georgia Medical Center & Health System, Inc. is accredited by the Medical Association of Georgia to provide continuing medical education for physicians. The Northeast Georgia Medical Center & Health System, Inc. designates this enduring activity for a maximum of 1.0 _AMA_ _PRA_ _Category_ _1_ _Credit_ ™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

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#ketodiet #ketodieting #ketorecipes #ketogenic : Secrets of Successful Weight Loss and Shortcomings The #ketogenic (keto) diet is a high-fat, moderate-protein, and low-carbohydrate diet that shifts the body into a metabolic state called ketosis. In this state, the body burns fat as its primary energy source, leading to rapid weight loss and improved metabolic health for some individuals. Pros of the Keto Diet: 1. Promotes quick weight loss by utilizing fat as fuel. 2. Reduces appetite, leading to fewer calories consumed. 3. May improve insulin sensitivity, blood sugar control, and metabolic markers. 4. Shows promise for neurological conditions, such as epilepsy. Cons of the Keto Diet: 1. Common initial side effects include the “keto flu” (fatigue, nausea, and headaches). 2. Long-term sustainability is challenging due to restrictive food choices. 3. Nutrient deficiencies, increased cholesterol, and risks to kidney/liver health can arise. 4. Social and lifestyle factors make adherence difficult for some individuals. The keto diet can be an effective tool for weight loss and certain health conditions, but it requires proper planning, monitoring, and consultation with healthcare providers. A balanced approach is key to maximizing benefits while minimizing risks. #healthcityvistaar #drkpchandra #drrajivawasthi #nitinranjangupta