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This is the story of how GLP-1 receptor agonist drugs like semaglutide and tirzepatide were developed. Support my work on Nebula: https://go.nebula.tv/patrickkelly ☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️ 🎬C R E D I T S🎬 Written, performed, and edited by Patrick Kelly Select imagery/video supplied by Getty Images Thank you to Dr. Svetlana Mojsov and Rockefeller Institute for the use of Dr. Mojsov's portrait 🔗 L I N K S 🔗 📱Instagram: https://www.instagram.com/patkellyteaches/ 💰Patreon: https://www.patreon.com/corporis 🔬Old channel: www.youtube.com/corporis/ 📚Book recommendations: www.patkellyteaches.com/books 🔑 P A T R O N S 🔑 Oxytocin Tier: Mike W | Paul R | Daphnanne P | Oliver W | Tal Globus | Paul Belmes Growth Hormone Tier: Carey & Jack P | Brendan P | Brandon K | Kristofer R | Joe B | Mindi F | Michael G | Brian B | Eileen H | Waffles the Dog | Brian T | Brian H | Michael R | Karen S | Sarah B | Robin B | Jacob S | Hyeon-Seo | Paul! | Lucy Fur | Huynhy | Jim C | elnombre91 | Alcedo | Josef K | Dab B | Robert M | Jiggs | TierZoo | Seth G | Jane G | Jack M | Matthew B | Michelle J | Helena SB | Eric L | Ryne J | Kilian | Dean M | Cody S | Michelle L | Joseph G | Aryan R | Vic K | Becca | Jesse B | Stella | Marc M | Roxanna A | Doyle V | Maria A | Karen S | Jon A | Brian | Blake | Caitlin E | David W | DrCredibleHulk | Eugene F | Anthony DiF | Charlie C | Reniece J | chris | Rachel J | ZoeMarie | Katie B-S | Broderic D | CJ 📜 S O U R C E S 📜 An annotated version of the script can be found on Patreon: https://www.patreon.com/posts/glp-1-video-133601476?utm_medium=clipboard_copy&utm_source=copyLink&utm_campaign=postshare_creator&utm_content=join_link Novo Nordisk (2023) by Kurt Jacobsen The discovery and development of GLP-1 based drugs that have revolutionized the treatment of obesity (2024) https://www.pnas.org/doi/10.1073/pnas.2415550121 Glucagon as the First Incretin: Objects (in the Rearview Mirror) Are Closer Than They Appear (2023) https://diabetesjournals.org/diabetes/article/72/12/1739/153849/Glucagon-as-the-First-Incretin-Objects-in-the The development of Byetta (exenatide) (2012) https://www.sciencedirect.com/science/article/pii/S0041010110004472 The time has come for incretins, a long time coming (2010) https://link.springer.com/content/pdf/10.1007/s00109-009-0586-5.pdf Dual GIP–GLP1-Receptor Agonists In The Treatment Of Type 2 Diabetes: A Short Review On Emerging Data And Therapeutic Potential (2019) https://www.dovepress.com/article/download/48870 Type 2 Diabetes https://diabetesatlas.org/media/uploads/sites/3/2025/02/IDF-Atlas-2nd-Edition.pdf https://diabetes.org/about-diabetes/type-1 https://www.ncbi.nlm.nih.gov/books/NBK507839/ https://www-sciencedirect-com.harker.idm.oclc.org/science/article/pii/S0169409X02000935?via%3Dihub FDA Shortages: https://www.fda.gov/media/185526/download?attachment 💻 C O N T A C T 💻 patkellyteaches [at] gmail.com ⌛T I M E S T A M P S ⌛ 0:00 intro 0:52 GLP-1 as a hormone 9:50 GLP-1 as a diabetes drug 13:00 exenatide 16:21 liraglutide 19:20 GLP-1 as an obesity drug 24:25 dulaglutide 25:23 semaglutide 28:40 tirzepatide 30:45 Compounding pharmacies 33:26 Conclusion #historyofmedicine #medicalhistory

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Shark Tank breakout: BioLyfe, creator of an innovative keto supplement, lands their deal with the sharks.Here’s their big announcement: Shark Tank breakout! For those who aren’t familiar with the show, BioLyfe is the first keto supplement company to ever appear on the hit ABC TV show Shark Tank. After pitching their innovative approach to the sharks, they successfully closed the deal and are now on the Shark Tank payroll. Another step closer to revolutionising the keto supplement market!

The Journey to Shark Tank

Before the episode of Shark Tank that put their keto supplements on the map, BioLyfe had already started to make a name for itself in the health and wellness industry. Their keto supplements were different than others on the market because they hadn’t been stripped of all their natural compounds. A dedicated customer base was already growing and enjoying the benefits of the supplements BioLyfe made. When the makers were approached by the producers of Shark Tank to pitch their business to the sharks, they knew they needed to expand.

BioLyfe had descended their podium at Shark Tank prepared to show the sharks their product line and tell them their story, why their products were superior, and how they were helping their customers reimagine what it meant to enjoy a meal. While the sharks were impressed with the quality of BioLyfe’s products and the passion of their team, another game began after their presentation. After a tense negotiation, a deal had been struck that changed the course of BioLyfe’s Shark Tank experience.

In the wake of Shark Tank, consumer interest in BioLyfe’s products has spiked. The visibility of a profile on an international stage helps this fledgling company to reach more customers, become a tastemaker in the keto supplement sphere, and negotiate a partnership with sharks that can help propel its business to the next level.

The Impact of Shark Tank

The exposure from the Shark Tank deal has been integral to BioLyfe’s business success, allowing them to scale up and diversify their offerings. Since Shark Tank, BioLyfe has been able to scale up to a much bigger team, increase production and expand its product line due to the new capital from its shark investors. It’s even branched out into a whole new range of keto supplements, allowing it to reach more customers who are seeking a more sustainable, stripped-back approach to their health.

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But coming up with the money for your company isn’t everything; sometimes, the expertise and contacts of the businesspeople behind it are critical. BioLyfe has benefited from the guidance and mentoring of the sharks, which have helped it grow and compete against rivals. Today, with the sharks championing BioLyfe in the market, the future has never looked brighter for the start-up.

To sum up, BioLyfe has been given a golden opportunity on Shark Tank, which helped them secure funds, breakthrough to various investors and improve and expand their business. Their novel products would give them a chance to disrupt the keto supplement industry. It also encourages them to improve their business performance to draw more attention from the market. In conclusion, enjoying massive popularity and dynamic expansion, BioLyfe is a company that is full of vitality. Their special products and passionate team are destined to make a difference in the world of health and wellness.

FAQ

Q: What makes BioLyfe’s keto supplements unique?

Q: So what ingredients and method are used to make BioLyfe’s keto supplements? A: BioLyfe’s whole-food keto supplements are made from the highest-quality ingredients available and are designed to help make keto ventures easier by assisting with fat loss and providing individuals subsistence when embarking on the ketogenic diet. Designed by a leading healthcare professional in the field of keto diet, these products are made from all-natural ingredients that help make ketosis easier and more successful.

Q: How can I purchase BioLyfe’s products?

A: BioLyfe products can be purchased on their website and are also available at select retailers. Keto supplements come in the form of powders, capsules, and snacks to help customers feel happy and healthy.

Q: What sets BioLyfe apart from other keto supplement companies?

A: Excellent products and trust set Biolyfe in a league of its own from other keto supply companies. Dedicated to being cutting edge and dependable, Biolyfe works to ensure their clients have the very best for existing and getting to the next level.

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I think I finally learned how to edit! I had to edit out my children fighting..lol.

Do Glp1 Medications Work Well For Women With Pcos Yes Glp1 Pcos Pcosweightloss

Yoga Pilates Reduce Belly Fat #weightlosstips #slimbelly #homefitness #shorts #exercise #motivation #fatloss #bellyburn #weightloss #slimbelly #bellyfatloss #homeworkout #challenge #homeworkout #fitness #gym #yoga #yogapilates #top2fit #healthcareworkout Disclaimer: - Under section 107 of the copyright Act 1976, allowance is mad for FAIR USE for purpose such a as criticism, comment, news reporting, teaching, scholarship and research. Fair use is a use permitted by copyright statues that might otherwise be infringing. Non- Profit, educational or personal use tips the balance in favor of FAIR USE. Socail Media Link Follow Me Facebook Link :- https://www.facebook.com/share/8SK3ndPEpVV27Qh2/?mibextid=qi2Omg Instagram Link :- https://www.instagram.com/health_care_workout?igsh=bDhvMzE4Z2lrbXRp

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#Kelly_Clarkson_reveals #medical_diagnosis #prompted_her_weight_loss
Kelly Clarkson says a diagnosis about her health motivated her to make some new choices.

During a recent episode of her daytime talk show, her guest Kevin James mentioned how well Clarkson is looking these days.

The singer and talk show host has previously talked about how walking in New York City, where she now lives and her show is based, has helped her shed weight and find new joy.“Well, I was told I was prediabetic,” Clarkson said, adding that she was not shocked by the diagnosis. “I was a tiny bit overweight.”

She said she was told, “You’re prediabetic, you’re right on the borderline.”

“I was like ‘But I’m not there yet,’” Clarkson joked.

The singer and talk show host said it took about two years before she was “ready to do something about it,” but she started listening to her doctors, adjusting her diet and getting more exercise.

According to the CDC, “prediabetes is a serious health condition where blood sugar levels are higher than normal, but not high enough yet to be diagnosed as type 2 diabetes.”

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Semaglutide is a medication that has gained attention for its potential to help with weight loss. It belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists, which are typically used to treat type 2 diabetes. However, recent studies have shown that semaglutide can also be effective in promoting weight loss in individuals who are overweight or obese.

How Does Semaglutide Work for Weight Loss?

Semaglutide works by mimicking the effects of a hormone called GLP-1, which is naturally produced in the body. GLP-1 helps regulate blood sugar levels by stimulating the release of insulin from the pancreas and reducing the production of glucagon, another hormone that raises blood sugar. In addition to its effects on blood sugar, GLP-1 also helps regulate appetite and food intake. By activating the GLP-1 receptor, semaglutide can help reduce hunger and promote feelings of fullness, leading to decreased calorie consumption and, ultimately, weight loss.

Studies have shown that semaglutide can lead to significant weight loss in individuals who are overweight or obese. In one study, participants who took semaglutide lost an average of 15% of their body weight, compared to just 2.4% in those who took a placebo. This weight loss was sustained over a 68-week period, suggesting that semaglutide can help individuals achieve long-term success in managing their weight.





When Does Semaglutide Start Working?

One of the most common questions people have about semaglutide is how quickly it starts working. While individual results may vary, many individuals begin to see weight loss within the first few weeks of starting treatment. In clinical trials, participants who took semaglutide typically began to lose weight within the first 4-8 weeks of treatment. However, it’s important to note that the rate of weight loss can vary depending on factors such as diet, exercise, and overall health.

It’s also important to keep in mind that weight loss with semaglutide is not immediate or guaranteed. While some individuals may see rapid results, others may experience slower progress. It’s essential to have realistic expectations and give the medication time to work. Additionally, incorporating healthy lifestyle changes such as a balanced diet and regular exercise can help enhance the effects of semaglutide and support long-term weight loss goals.

Are There any Risks or Side Effects?

Like any medication, semaglutide carries some risks and potential side effects. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and tend to improve over time as the body adjusts to the medication. However, if you experience severe or persistent side effects, it’s essential to contact your healthcare provider.

In rare cases, semaglutide has been associated with more serious side effects, such as pancreatitis and thyroid tumors. It’s crucial to discuss the risks and benefits of semaglutide with your healthcare provider before starting treatment. They can help determine if semaglutide is the right choice for you based on your individual health profile and weight loss goals.

How Long Should Semaglutide be Taken for Weight Loss?

The duration of treatment with semaglutide for weight loss can vary depending on individual goals and response to the medication. In clinical trials, participants typically took semaglutide for a period of 68 weeks to achieve significant weight loss. However, some individuals may benefit from longer-term treatment to maintain weight loss and continue seeing results.

It’s essential to work closely with your healthcare provider to determine the appropriate duration of treatment with semaglutide. They can help monitor your progress, adjust your dosage as needed, and provide guidance on how to maintain weight loss results once treatment is completed. By following their recommendations and making healthy lifestyle choices, you can maximize the benefits of semaglutide for weight loss.

Overall, semaglutide shows promising results as a potential treatment for weight loss in individuals who are overweight or obese. By mimicking the effects of the hormone GLP-1, semaglutide can help reduce hunger, promote feelings of fullness, and support long-term weight loss goals. While individual results may vary, many people begin to see weight loss within the first few weeks of starting treatment. It’s essential to manage expectations, stay committed to healthy habits, and work closely with your healthcare provider to maximize the benefits of semaglutide for weight loss.

Where To Buy Shark Tank Keto Gummies A Buyers Guide

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