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In this episode, we dive into groundbreaking research on GLP-1s and other hunger hormones and how a clinically studied plant compound is helping women reduce cravings, improve appetite control, and support fat loss—naturally. You'll learn how bitter compounds work with your gut-brain axis, why your hunger hormones may be out of sync, and how this New Zealand–funded discovery is changing the game for women coming off GLP-1 injectables like semaglutide or tirzepatide. #GLP1 #FatLossForWomen #CravingControl #WomensMetabolism #BiohackingWomen 👉 Get 10% off, use discount code: 10OFF to purchase Calocurb @ https://www.calocurb.com/optimized10 🔑 KEY TOPICS 🔑 -GLP-1, CCK & PYY: how they control hunger -Bitter compounds and the gut-brain axis -Clinical trial results on female hunger and cravings -Supporting women off GLP-1 injections -Protein, probiotics, and stacking supplements for appetite 🕐 TIMESTAMPS 🕐 [00:00] Why hunger isn't about willpower: The role of ghrelin and the hindbrain [03:00] Government-funded research on natural appetite suppressants from bitter compounds [10:15] How GLP-1, CCK, and PYY regulate appetite and fat loss through the gut-brain axis [16:00] Women’s unique hormonal response to GLP-1 and why female trials matter [20:30] Reducing cravings and calorie intake during PMS and the luteal phase [27:30] Transitioning off GLP-1 injectables with natural gut-based solutions [34:00] Best supplements to stack with Calocurb: protein, probiotics, amino acids [40:00] Clinical results on weight loss, fat vs muscle, and upregulating GLP-1 [43:00] How to spot scammy weight loss supplements vs real research-backed solutions 🎙️Guest: Sarah Kennedy🎙️ Website: https://www.calocurb.com/optimized10 👉 Get 10% off, use discount code: 10OFF to purchase Calocurb 🌐 LET'S CONNECT 🌐 Host: Orshi McNaughton Podcast Links: https://linktr.ee/optimizedwomen Website: https://www.optimizedwomen.com/ YouTube Channel: https://www.youtube.com/@optimizedwomen Instagram: https://www.instagram.com/optimizedwomen Enjoying the podcast? ⭐️⭐️⭐️⭐️⭐️ Don’t forget to subscribe and leave a review to help spread the word! 🎵 MUSIC CREDIT 🎵 "Power Play" by Top Flow (https://pixabay.com/users/top-flow-28521292) Licensed under Pixabay License (https://pixabay.com/service/terms)

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Please Subscribe for 3x Videos Per Week https://www.youtube.com/user/TheTdelauer?sub_confirmation=1 To learn more, visit my website here: http://www.ThomasDeLauer.com Get the Apparel I Wear at http://www.Hylete.com Weight Loss | How Fat Burning Works | Lipolysis Explained– Thomas DeLauer… So you want to burn fat - what exactly does that mean? In order to burn fat most efficiently, it is important to first understand how fat metabolism works. Fat must be released from our cells. Only once the fat has been released can it be burned and used for energy. The majority of fat in our bodies resides in fat cells. These cells are made up of roughly 15% lean mass and 85% fat, in the form of a lipid droplet. To use this fat we must get it to cross over the cell membrane of the fat cell. This process is called lipolysis. An enzyme called hormone-sensitive lipase takes a triglyceride, the fat in the cell, and separates the three fatty acids from the glycerol. This frees the fatty acids to pass through the cell membrane to be made available to the Krebs Cycle. So to use your stored fats as fuel, you need to produce hormone-sensitive lipase. Many hormones are involved here, but the one that you want to be most concerned with is insulin. If you have high levels of insulin in your blood, you are going to have low levels of lipase. Dietary carbohydrates are the main contributor to your blood insulin levels. So how do we burn our stored fat? The Krebs Cycle: You may remember from biology class the Citric Acid Cycle, also known as the Krebs cycle. Mitochondria are found in the hundreds to thousands in all cells in our body (except mature red blood cells). Here, energy from what we eat, the carbohydrates, fats and proteins, are converted into ATP. Acetyl COA is used to form the energy, or ATP, in the Krebs cycle: If you are consuming carbohydrates or eating too frequently, your blood is going to have high insulin levels and there will be carbohydrates that you have recently eaten available as the fuel for the Krebs Cycle. Traditionally, carbohydrates that you eat are broken down in your body. The glucose undergoes a process called glycolysis and pyruvate is formed. In the mitochondrial matrix, pyruvate undergoes oxidation and ACOA is formed. ACOA can also be formed from the breakdown of fats and amino acids, or the building blocks of proteins. How your body uses its energy is dependent upon what you eat. Traditionally, when you are in a normal state, your body is using carbohydrates for their main energy source through the citric acid cycle. If you change how you eat, you can train your body to instead form ACOA through the breakdown of ketone bodies. How Does it Work? When glucose is in short supply, your body begins lipolysis. These free fatty acids, rather than carbohydrates from your food, are used to produce ACOA. Once the fatty acids have been released into your bloodstream, they bind to a protein called albumin. Albumin shuttles the fatty acids to the muscle cells where they are taken into the mitochondria as ACOA. In very fit athletes the muscle cells themselves will begin to store the lipid droplets in them rather than glucose for immediate energy fuel. Lipogenesis: When you eat carbohydrates, they break down into glucose in your blood. The pancreas secretes insulin to shuttle the glucose out of the blood and into either the muscle or liver for immediate use, glycogen storage, or they be stored as fat. Your liver and muscle cells have a limited capacity for glycogen storage that is not very high. This means that when you consume excess carbs your body has to store them as fat through a process called lipogenesis. Simply put, lipogenesis is the creation of fatty acids from carbohydrates that you consume. While for our ancestors in the hunting and gathering days this storage of energy was great, in the age of abundance we are struggling with the health impacts of storing excess fat. This fat storage follows a process very similar to the Krebs Cycle discussed. Once the ACOA is created, if the body does not need to use it for energy or for storage in the muscles and liver, it is stored through lipogenesis as fat for later use. References: 1. The Citric Acid Cycle https://www.khanacademy.org/science/biology/cellular-respiration-and-fermentation/pyruvate-oxidation-and-the-citric-acid-cycle/a/the-citric-acid-cycle 2. The citric acid cycle oxidized two-carbon units http://www.ncbi.nlm.nih.gov/books/NBK22427/ 3. What is Ketosis? Our article :) 4. Fat Breakdown and Fat Burning: Lipolysis and Oxidation http://leanmessengers.com/fat-breakdown-and-fat-burning-lipolysis-and-oxidation/ 5. How and what am I digesting? A breakdown of macronutrient… http://leanmessengers.com/?s=lipogenesis 6. Lipid catabolism summary http://chemistry.elmhurst.edu/vchembook/622overview.html 7. Acetyl COA - Crossroads Compound http://chemistry.elmhurst.edu/vchembook/623acetylCoAfate.html

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In recent years, the health and wellness industry has seen a surge in the popularity of dietary supplements that promise to assist in weight loss and overall health improvement. Among these, Activ Boost Keto ACV Gummies have emerged as a notable player, combining the benefits of the ketogenic diet with the renowned advantages of apple cider vinegar (ACV). This unique product is designed to help individuals seeking to shed pounds while maintaining optimal energy levels and metabolic function. The growing awareness of keto diets, which emphasize high fat and low carbohydrate intake, paired with the purifying effects of ACV, creates a promising formula. Many enthusiasts and individuals looking for weight loss solutions flock to these gummies, drawn by the idea that they offer a simpler and more enjoyable way to incorporate these health benefits into their daily routine. How Your Body Loses Weight

But what exactly are Activ Boost Keto ACV Gummies? At their core, these gummies are crafted to utilize the principles of ketosis—a metabolic state where the body burns fat for fuel instead of carbohydrates. During this state, the body produces ketones, which serve as an alternative energy source, leading to increased fat loss and improved mental clarity. The incorporation of apple cider vinegar into this equation may enhance the overall effectiveness of the gummies by improving digestion, promoting blood sugar control, and contributing to appetite suppression. This dual-action approach makes these gummies not just a weight loss aid but potentially a holistic health supplement.

The convenience of consuming gummies as opposed to traditional pills or powders cannot be understated. Many individuals find it easier to adhere to a regimen that includes tasty gummy supplements—adding a little sweetness to their journey toward health. The makers of Activ Boost Keto ACV Gummies have capitalized on this trend by creating a product that is both palatable and effective. In addition to their flavor and texture, the nutritional profile of these gummies is often enhanced with vitamins and minerals that support overall health. As we delve deeper into this article, we will explore the efficacy, expected results, testimonials, and any potential concerns surrounding these gummies. Ultimately, our goal is to provide a comprehensive analysis to help you determine whether Activ Boost Keto ACV Gummies are a worthy addition to your dietary strategy for weight management and wellness.

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Discover the top natural ways to increase your GLP-One levels, including fiber, prebiotic, probiotic foods, and antioxidants. Learn about the potent effects of thylakoids and their impact on GLP-One secretion. Watch now for a comprehensive guide. #GLPOneLevels #NaturalFoods #FiberBenefits #Prebiotics #Probiotics #Antioxidants #Thylakoids #BloodSugarControl #HealthyLiving #DigestiveHealth

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